Found 45 matching trials
A Combination of Acalabrutinib With R-CHOP for Patient Diffuse Large B-cell Lymphoma (DLBCL) PHASE1 Previously untreated CD20 positive diffuse large B-cell lymphoma (DLBCL) re...
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Southampton University Hospitals NHS Tust
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Zanubrutinib (BGB-3111) in Participants With Previously Treated B-Cell Lymphoma Intolerant of Prior Bruton Tyrosine Kinase Inhibitor (BTKi) Treatment PHASE2 The primary objective of this study is to evaluate the safety of zanubrutin...
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Rocky Mountain Cancer Centers (Williams) Usor
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A Study to Evaluate Relative Bioavailability, Proton Pump Inhibitor (PPI) (Rabeprazole) Effect, Food Effect and Particle Size Effect of New Acalabrutinib Tablet in Healthy Subjects PHASE1 This study will be a 2-part, open-label, single-center relative bioavailabi...
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Assessing a ctDNA and PET-oriented Therapy in Patients With DLBCL A Multicenter, Open-label, Phase II Trial. PHASE2 Within this exploratory multicohort phase II trial, SAKK aims to evaluate a...
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Active Not Recruiting
Location
Ospedale Papa Giovanni XXIII
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Acalabrutinib in Patients With Relapsed/Refractory and Treatment naïve Deletion 17p CLL/SLL PHASE2 This study is to determine the response to acalabrutinib in patients with c...
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A Comparison of Three Chemotherapy Regimens for the Treatment of Patients With Newly Diagnosed Mantle Cell Lymphoma PHASE2 This phase II trial compares three chemotherapy regimens consisting of bend...
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Active Not Recruiting
Location
Anchorage Associates in Radiation Medicine
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Study of BTK Inhibitor LOXO-305 Versus Approved BTK Inhibitor Drugs in Patients With Mantle Cell Lymphoma (MCL) PHASE3 This is a study for participants with a type of blood cancer called mantle ...
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Active Not Recruiting
Location
Alaska Oncology and Hematology, LLC
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A Study of Tazemetostat in Combination With Various Treatments in Participants With Blood Cancer. PHASE1 This trial will study how safely the tazemetostat works with other therapie...
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California Cancer Associates For Research And Excellence, cCARE
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Acalabrutinib Plus RICE for Relapsed/Refractory DLBCL PHASE2 To evaluate the tolerability,feasibility, and efficacy of combining acalabr...
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Swedish Cancer Institute
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A Study of Nemtabrutinib (MK-1026) in Participants With Relapsed or Refractory Hematologic Malignancies (ARQ 531-101/MK-1026-001) PHASE1 This study aims to evaluate the safety, tolerability, pharmacodynamic, and ...
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Active Not Recruiting
Location
Mayo Clinic Hospital ( Site 0140)
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